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Vascular Research
the causes & treatment of serious disease of arteries & veins that blocks circulation anywhere in the body

The study of the causes and treatment of the serious disease of the arteries and veins that blocks circulation anywhere in the body

New technology has opened up exciting opportunities for translational research, aiming to better understand fundamental mechanisms in the cell and molecular biology of the vascular system and to develop new treatments to combat vascular disorders where unmet needs exist. Nikon’s A1R MP+ multiphoton and confocal systems enable deep tissue imaging to analyse vasculature formation and disease in vivo.  Nikon’s Eclipse Ti inverted microscope and Eclipse Ni upright microscope provides the fundamental framework for these confocal and multiphoton systems as well as many other imaging systems such as high content, field scanning confocal, and TIRF.  Nikon also provides super-resolution imaging systems, the N-SIM and N-STORM, for ultra-high resolution, nanoscale imaging.  For macro imaging, Nikon provides a multizoom microscope, the AZ100 Multizoom, as well as a suite of large zoom range stereomicroscopes.  For clinical diagnosis and cytopathology, the Eclipse Ci microscope with its ergonomic and compact design is ideally suited. Combined with the Digital Sight series cameras and network-capable image acquisition system, the DS-L3, real-time image sharing to clinicians in remote locations, also known as telepathology, is possible.

Imaging Challenges

How do I image thick samples?

Nikon’s A1 MP+ multiphoton microscope with long excitation wavelengths up to 1300nm enable deep tissue penetration with reduced light scatter.  Nikon’s Eclipse FN1 microscope provides a flexible structure that can be optimized to accommodate large or thick samples.

SOLUTION

How do I image the fast movement of cells in vascular tubes?

High-speed imaging is possible with Nikon’s A1r+ MP confocal and multiphoton microscope by using its resonant scanners

SOLUTION

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