the study of hormones and the endocrine system
The study of hormones and the endocrine system
Although the diagnosis and treatment of endocrine diseases are guided by laboratory blood tests to a large extent, microscopic examination of endocrine tissues plays an important role. Changes in tissue and cell structure and the diagnostic challenges in differentiating between benign and malignant endocrine tumours can be investigated using immunohistochemical markers, for example, with Nikon’s new ergonomic Eclipse Ci clinical upright microscope range. Telepathology/cytology technologies also greatly assist in real-time assessment of biopsies by pathologists in remote locations, in training, and archiving specimens. Nikon’s Digital Sight series cameras and DS-L3 imaging system enable clinics to implement telepathology with ease. Advanced imaging systems such as Nikon’s Eclipse Ti inverted microscope, the Eclipse Ni upright microscope series, the AZ100 Multizoom upright zoom microscope and the powerful A1R+ / A1+ confocal laser microscope systems with enhanced spectral imaging, together with specialised objectives, enable the visualisation of specific cellular and receptor mechanisms in endocrinology. In addition, these microscope systems are ideal for live-cell imaging to provide critical insight into the fundamental nature of the signalling pathways and function of tissue regulatory factors. Fluorescent probes allow monitoring of protein expression, locating and tracking molecules and identification of intermolecular interactions. Multiple probes may be used simultaneously and identified with high resolution using spectral imaging capabilities.