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In the News

Key to cancer?

October 31, 2013

Researchers have demonstrated the importance of a newly identified protein, called Bod1, which is required for proper chromosome alignment at mitosis, to enable cancer cells to grow and divide. When this protein is removed cancer cells lose control of cell division and die. The study also discovered that Bod1 works by co...

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Zebrafish models human defects

October 17, 2013

Copy-number variants (CNVs), fragments of the genome that are either missing or existing in extra copies, are quite common.  Their precise contribution to diseases, however, has been difficult to determine because CNVs can affect the function of many genes simultaneously.  A new study has duplicated complex hum...

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New treatment strategies in neurodegeneration

September 15, 2013

Defects in DNA repair have been extensively linked to neurodegenerative diseases, but the exact mechanisms remain poorly understood. A study has found new evidence that suggests that a failure to repair damaged DNA could underlie not only Amyotrophic lateral sclerosis (ALS), but also other neurodegenerative disorders suc...

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Autoimmune disease prevention

September 9, 2013

A study has identified an immune cell, extrathymic Aire-expressing cells (eTAC), which may help prevent autoimmune diseases. These cells which are relatively rare and found in lymph nodes and the spleen contain a protein in their nucleus called AIRE. The study also determined that eTACs counteract the overactive immune r...

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Non-mammalian cells reprogrammed

September 5, 2013

Cells are fundamental units of life, but little is known about evolution of cell states. Induced pluripotent stem cells (iPSCs) are once differentiated cells that have been re-programmed to an embryonic stem cell-like state, providing a powerful platform for biology and medicine. However, they have been limited to a few...

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Socially anxious mice see the light

August 29, 2013

Serotonin modulates neural responses to socioaffective cues and can bias approach or avoidance behavioural decisions. A study has discovered the neurons that inhibit the release of serotonin and can lead mice to become socially anxious when they are bullied. The research identified that a class of GABA neurons (gamma ami...

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Neuronal circuit polarity

August 13, 2013

Nerve cells (neurons) have a highly asymmetric shape, with a long, trunk-like extension (axon). Branch-like structures (dendrites) sprout from the opposite end of the cell body. Neuronal networks are formed by connecting dendrites to axons.  A recent study has found that embryonic nerve cells produce two versions (i...

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Mouth microbe turns cancerous

August 13, 2013

Fusobacterium nucleatumis a Gram-negative oral microbe with the potential to become pathogenic, occasionally causing periodontal disease. Two new studies present functional evidence to help explain how F. nucleatum spurs the development of colorectal cancer (CRC).One study using a mouse model of intestinal tumorigenesis...

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Compartmentalising Alzheimer’s triggers

August 8, 2013

The convergence of amyloid precursor protein (APP) as a substrate and beta-secretase (BACE-1) enzyme is a rate-limiting, obligatory event triggering the amyloidogenic pathway, a key step in Alzheimer’s disease (AD) pathology. However, as both APP/BACE-1 are highly expressed in brain, mechanisms maintaining their critical...

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Light control of genes

July 25, 2013

A new light technology has been developed that offers the ability to precisely control the timing and duration of gene expression simply by shining light on the cells. Based on a technique known as optogenetics, which uses proteins that change their function in response to light, light-inducible transcriptional effectors...

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Jul 22, 2013 Breakthrough blindness stem cell study
Jul 12, 2013 Cancer development though cell cycle disruption
Jul 3, 2013 Grow your own liver
Jun 13, 2013 Role of nervous system in arthritis
Jun 2, 2013 Vinegar test spots early cervical cancer in India
May 20, 2013 Mucus role as anti-bacterial
May 17, 2013 A Shout Out for the Scallop
May 15, 2013 Expanding the Brainbow toolbox
May 9, 2013 Malaria control?
Apr 30, 2013 A nose for diagnosis
Apr 25, 2013 Cancer killing efficiency captured on video
Apr 8, 2013 A Look at Live Cell Imaging: Introducing Perfect Focus
Mar 29, 2013 Stem cells get a grip
Mar 24, 2013 New Down’s syndrome protein found
Mar 9, 2013 Cultured teeth a possibility
Mar 7, 2013 Glial cells make you cleverer
Mar 3, 2013 Misfolded proteins in degenerative diseases
Feb 25, 2013 Using magnetism to study metastases
Feb 21, 2013 Tiny architects offer therapy potential
Feb 11, 2013 Preventing metastasis
Feb 1, 2013 Mass transit
Jan 28, 2013 First aid stem cells
Jan 21, 2013 Quadruple DNA helix revealed
Jan 16, 2013 Social chromosome identified
Jan 10, 2013 Sickle cells – the grim reaper for cancer?
Dec 17, 2012 Urate involved in PD?
Dec 5, 2012 Repairing a broken heart
Nov 14, 2012 Fresh hope in infertility
Nov 8, 2012 Inflammation leads to regeneration
Oct 24, 2012 Eliminating mtDNA mutations
Oct 17, 2012 Breakthrough in Parkinson’s pathology
Sep 13, 2012 Diabetes cell transformation
Aug 1, 2012 Evidence for the existence of cancer stem cells
Jul 25, 2012 Turning the clock back for aged heart cells
Jul 17, 2012 Stress can lead to metastasis in breast cancer
Jul 9, 2012 Animal magnetism
Jun 27, 2012 Not so cool dinosaurs
Jun 13, 2012 Mapping the microbiome
Jun 12, 2012 Lazarus stem cells
Jun 7, 2012 Fewer tumour mtDNA mutations
May 29, 2012 True tissue engineering
May 23, 2012 Transplant to treat pain
May 14, 2012 Moonlighting protein could cause defects
May 9, 2012 New Inflammatory target
May 3, 2012 Protecting the protectors
Apr 27, 2012 Bird brain satnav
Apr 19, 2012 Manmade evolution
Apr 11, 2012 Brain injuries help map intelligence
Apr 4, 2012 Hope for a HCV vaccine
Mar 21, 2012 Help for male baldness may be in sight
Mar 9, 2012 Enhancing drug effects
Mar 2, 2012 Memories are made of this
Feb 28, 2012 Early events in Alzheimer’s
Feb 14, 2012 Helping a healthier heart
Feb 8, 2012 Neighbourhood watch
Jan 26, 2012 Cloak of invisibility?
Jan 24, 2012 An eye to the future?
Dec 15, 2011 Results of Nikon-sponsored First World Cell Race
Nov 10, 2011 Patient, heal thyself
Jul 31, 2011 The secret of youth?
Jul 19, 2011 Shining a light on Alzheimer’s
Jul 14, 2011 Successful synthetic tissue engineered windpipe
Jul 5, 2011 Muscle building
May 27, 2011 Monkey mind control may help ADHD
May 14, 2011 PC power helps fight flu
May 13, 2011 Dutch funding boosts super-resolution microscopy
May 11, 2011 Hope for liver repair
May 3, 2011 Turning bad fat into good – hope for obesity?
Apr 21, 2011 Chimeras more common?
Apr 14, 2011 Brain healing
Apr 13, 2011 Older than you think
Apr 6, 2011 Keeping an eye on retinal developments
Mar 20, 2011 Autistic mice raise hope for treatments
Mar 16, 2011 Secrets of sperm offer contraceptive developments
Mar 7, 2011 Life in 3D
Feb 19, 2011 Helping IVF success
Feb 1, 2011 Broken hearted zebra fish
Jan 19, 2011 Renal cancer gene identified

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