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Super-Resolution Microscope System

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Ten times the resolution of conventional optical microscopes.

N-STORM is a super-resolution microscope system that combines “STochastic Optical Reconstruction Microscopy” technology (licensed from Harvard University) and Nikon's Eclipse Ti research inverted microscope. The N-STORM super-resolution microscope provides dramatically enhanced resolution that is 10 times that of conventional optical microscopes.

Key Features

Ten Times the Resolution of Conventional Optical Microscopes

N-STORM utilizes a high accuracy localization information for thousands of individual fluorophores present in a field of view to create breathtaking super-resolution images exhibiting spatial resolution of 20nm; ten times greater than conventional optical microscopes.


3D Imaging with 50 nm Axial Resolution

In addition to lateral super-resolution, N-STORM utilizes proprietary methods to achieve a tenfold enhancement in axial resolution to 50nm, effectively providing 3D information at a nanoscopic scale.

Fluorescence labeled microtubule

3D-STORM image of antibody-labeled microtubules. Colors encode z-depth information.

Image Construction by Overlaying Single Molecule Images

Image Construction by Overlaying Single Molecule Images

“STORM” is a new technology that reconstructs high resolution fluorescence images (2D or 3D) from localization information of fluorophores detected with high accuracy and calculated from multiple exposures. This technique generates much more detailed information and goes one step further, from structural to molecular understanding of the specimen.

Unique Multi-color Technology

Multi-color super-resolution imaging can be carried out using several dye strategies. Unique tandem dye pairs that combine "activator" and "reporter" probes allow highly accurate localization with no z shift.

Combination with A1R+


The N-STORM system is based around the Nikon Ti-E inverted microscope. This flexible platform allows combination with confocals such as the A1R+ for live-cell imaging, low magnification observation, photo-stimulation and 20nm-resolution imaging on one integrated system, under the control of the universal NIS-Elements platform.

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